Vice President of Clinical Science, Neurology

Clinical     ·      San Francisco, CA     ·     Full time

At Alector, our mission is to develop therapies that empower the immune system to cure neurodegeneration. Our team is solely focused on developing cures for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and board members, leading healthcare investors and some of the most innovative pharma companies.

The Vice President of Clinical Development, Neurology will lead one or more development programs involving drug candidates in Frontotemporal Dementia, Amyotrophic Lateral Sclerosis and other diseases. You will be responsible for clinical strategies and plans for our lead molecules and help ensure the successful execution of our studies.

Reporting to the Senior Vice President of Clinical Development, the Vice President of Clinical Development will be a member of the Alector leadership team. The direct responsibilities of this position will cover Phase 2, Phase 3 and post-approval activities. This includes responsibility for advancing priority clinical programs through study planning and execution, development of biomarker strategies, as well as interpretation of data from these studies. You will interact with multiple levels of management within Alector, key external partners in the medical and scientific community, along global regulatory authorities.

The Vice President of Neurology has the Following Responsibilities:

• Provide leadership for programs that integrate the individual’s extensive knowledge in basic and clinical science, neurology disease areas with knowledge from the medical community around the world.
• Design and execute late-stage development programs in neurodegenerative disease including FTD and ALS
• Manage the preparation and/or review of data listings, summary tables, study results, study reports, and clinical/regulatory/safety documents, investigator brochures, and clinical development plans
• Integrate the scientific rationale, regulatory and payor requirements, input and advice from medical and patient advocacy groups, product development plan, and commercial goals to build a strategic framework for the Clinical Development Plan (CDP).
• Establish ambitious clinical development timelines, incorporating key decision points and Go/No Go criteria for each CDP.
• Develop and maintain collaborative relationships with program counterparts in Commercial, Research, Regulatory, Biomarkers, Clinical Operations, and Biometrics.
• Collaborate with Medical Affairs in developing educational materials and publication strategy.
• Engage with leaders, investigators, collaborative groups, and other specialists in scientific and clinical dialog around study design, study conduct, and interpretation of clinical results

You Will Have the Following Mix of Professional and Personal Characteristics:

• Minimum 12+ years Biotech/Pharmaceutical Industry experience, including 6+ years in Clinical Development; experience in rare diseases a plus
• Deep understanding of basic science related to neurodegeneration and immunology
• Capacity and willingness to work successfully across disease areas.
• Demonstrated leadership and team-building skills, including strong decision-making, conflict resolution, and analytical skills
• Demonstrated strategic and innovative thinking
• Excellent communication skills (oral and written) and organizational skills

Education:

• MD / PhD or DO credentials. Neurology training with sub specialization in degenerative CNS disorders preferred.

At Alector, we believe that high-performing teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, disability status, or any other characteristics protected under applicable federal, state, or local laws.

Alector is a great place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a cure, where you’ll drive growth, this is the role for you. There is no limit to how far you can go with us.

Benefits:

While we’ve focused on what to look forward to during the first year and beyond, Day One is great, too: committed and driven colleagues, a bold and important company goal, state-of-the-art brand-new brightly-lit offices in the heart of the biotech area, competitive compensation and benefits. But these matter only if you’re excited to build and own something great, and take on these challenges with us. Come join us.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please click here to apply.