Senior Research Associate, IHC Core

Biology        ·       South San Francisco, CA       ·       Full time

At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration. Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

As Research Associate for the IHC Core, you will contribute to the breadth of ongoing preclinical studies in support of our therapeutic discovery efforts. You will need to bring your experience in immunohistopathology expertise to support and maintain a new IHC Core function for the Alector Research organization. Teamwork and functioning within matrix structures will be important for successful collaborative efforts. 

You will be working with a Sr. Scientist and share responsibility for conducting novel and routine processes for immunohistochemistry, analyses, and image acquisition. You should feel comfortable working with teams managing the effort in start-to-finish IHC-based assessments across teams.

Key responsibilities include shared management of daily operations, participation in ongoing research projects, and coordination of projects during IHC processing efforts. 

During your first year, your goals will be:

• Demonstrate practical knowledge and current techniques with Microscopy and image analysis for the pre-clinical research department
• Enhance imaging strategy through their knowledge of programming (C++, Python, Matlab and R), machine learning, data integration and implementation of novel technologies and methodologies.
• Share knowledge and educate teams on the current Core practices on immunohistochemistry techniques (IHC, multiplex IF, etc), imaging and computational tissue image analyses
• Write protocols, technical reports, SOPs and develop appropriate documentation with project team(s) and collaborators.
• Share responsibility in maintaining IHC Core that enables efficient work-flow from in vivo studies through data analytics on pre-clinical IHC specimens
• Provide support for image capture an analysis using established software

We’d love to hear from you if:

• Bachelors or Master’s degree with 2 years experience in this space
• Breadth of experience with tissue processing with and without embedding for fresh frozen, fixed and cryopreserved, fixed for paraffin blocks
• Detail oriented practices and able to work collaboratively on complex projects across the organization
• Interest in learning about neuroscience and neurodegenerative disorders
• Strong interpersonal communication skills
• Experience with imaging software like Zen black, iMARIS, image J is desirable.
• Experience coding in python, MATLAB, or R or showing the ability to learn new programming languages is plus

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Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a treatment, where you’ll drive growth, this is your role. There is no limit to how far you can go with us.

Among the things you’ll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly-lit offices in the heart of the biotech area, flexible remote work options, and competitive compensation and benefits. But these matters only if you’re excited to build and own something great, and tackle these challenges with us. Come join us!

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief. 

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please click here to apply.