Associate Scientist, Mass Spec & Analytical Development

Process Development        ·        Newark, CA       ·       Full time 

At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration. Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

Use your scientific skills to help us achieve our mission of saving lives by curing neurodegenerative diseases. You will identify and provide support for ongoing programs and your work will be central to Alector’s strategic goals. You will be influential in championing and developing Alector’s culture and values.

As an Associate Scientist, you will be part of an Analytical Development Team and will work closely with Analytical team members. Communication and dedication are key aspects required in this role. You will have the opportunity to work with cross-functional members across multi-discipline departments and multi-levels including cell culture, upstream, purification, discovery, pre-clinical, and research.

The successful candidate should have a strong foundation and be very experienced with mass spectrometry operations and methodologies as well as be familiar with various chromatography methods such as Affinity, SEC, IEX, HIC, RP-HPLC. 

We’d love to hear from you if you have:

• Mass spectrometry analysis of early and late-stage, research biomolecules and biologics in support of internal discovery efforts and phase appropriate IND/BLA filings.
• Assist in perform analytical method developments for various or leading drug candidates.
• Carry out formulation stability studies for new molecules from research to critical reagents.

We’d love to hear from you if you have:

• A BS in scientific discipline e.g. chemistry, biochemistry, with 8+ years of related experience or a MS in scientific discipline e.g. chemistry, biochemistry, with 4-8 years of related experience
• 3-5 years of hand on experience in mass spectrometry.
• Strong hands-on experience using Mass Spectroscopy (specifically Orbitrap) to characterize monoclonal antibodies, bi-specific molecules, and new modalities.
• Hands-on experience in HPLC chromatography development work including RP, HIC, IEX, SEC.
• Hands-on experience in protein characterization and formulation stability.
• Demonstrated ability to design, execute and analyze experiments independently.
• A team player attitude, willing to work together, and share in knowledge and work accomplishments.
• Managerial / mentorship experiences is a plus.
• Strong and effective interpersonal skills with manager, in a team environment, and with cross-functional groups.
• Create and develop a culture of open communication and trust.
• Strong organizational skills and a strong attention to details.
• Ability to prioritize work to support drug development, meet deadlines, and timeframes.
• Effective work ethics and dedicated to completing challenging projects.
• Strong problem-solving capabilities.
• Effective technical writing skills for authoring technical documents, including Comparability Studies, GLP Studies, Qualification Studies.
• Prepared and presented scientific results at meetings.

#LI-RS1

#LI-Onsite

Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a treatment, where you’ll drive growth, this is your role. There is no limit to how far you can go with us.

Among the things you’ll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly-lit offices in the heart of the biotech area, flexible remote work options, and competitive compensation and benefits. But these matters only if you’re excited to build and own something great, and tackle these challenges with us. Come join us!

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief. 

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please click here to apply.