Pharmacology Scientist Manager

Research & Development    ·      Oxford / Cambridge / London / Manchester / Kent  ·       Full time

• Multiple Locations: Oxford, United Kingdom; Cambridge, United Kingdom; London, United Kingdom; Manchester, United Kingdom; Kent, United Kingdom
• Categories: Research & Development
• Req ID: 6747

Job Description

Jazz Pharmaceuticals plc (NASDAQ: JAZZ) is a global biopharmaceutical company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases – often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines and novel product candidates, from early- to late-stage development, in neuroscience and oncology. We actively explore new options for patients including novel compounds, small molecules and biologics, and through cannabinoid science and innovative delivery technologies. Jazz is headquartered in Dublin, Ireland and has employees around the globe, serving patients in nearly 75 countries. For more information, please visit www.jazzpharmaceuticals.com and follow @JazzPharma on Twitter.

About the Role

The Pharmacology Scientist Manager is responsible for managing and supporting pharmacology projects from conceptualisation and study design through to delivery of study report finalisation, and subsequent scientific publications, as well as inclusion into regulatory documentation. 

Responsibilities

• Generates new pharmacology data to the required standards and upon which the company may build and provide a rationale for pipeline progression and product development in the Neuroscience therapeutic area.
•  Provides strategic input into Preclinical goals and activities or functional goals and activities.
• Ensures preclinical pharmacology studies are run in accordance with the appropriate company, CRO or researchers SOPs, relevant regulatory guidelines, legislation and departmental processes as required per study.
• Supporting the Associate Director within the Discovery Pharmacology function, and in collaboration with other Preclinical Managers & Senior Managers, coordinates and reviews Preclinical Pharmacology team contributions to scientific and regulatory documents as required to meet corporate needs, including individual contribution as needed and consistent with the post-holder’s scientific expertise.
• Maintains good working relationships with contracted parties (AROs/CROs) on planned and in-life pharmacology studies, as well as with relevant key opinion leaders and researchers.
• Defines and manages study resource needs and establishes contingency plans for key resources.
• Leads, manages and provides technical input into scientific reports from CROs/AROs.
• Ensures that regulatory, pharmacovigilance and medical affairs documents are available and up-to-date as required, to meet corporate needs.
• Contributes to Function and/or Programme Teams as determined within the governance matrix structure.
• Responsible for maintaining own and direct reports cGxP and H&S knowledge applicable to the job.

Requirements

• A degree (BSc) and either higher degree (PhD or MSc) in Neuroscience, Pharmacology or another appropriate scientific discipline with relevant experience.
• Strong industry experience in a similar role.
• Experience or knowledge of translational biomarker techniques (e.g. imaging, EEG, ‘omics), PK/PD relationships and /or in vivo models of behavioural pharmacology in neuroscience would be desirable.
• Strong experience at pharmaceutical companies and/or CROs, regarding outsourcing of preclinical studies, vendor/client management and interfacing with internal Finance and Legal groups
• Experience with driving the timely delivery of clear, accurate and well written nonclinical data in finalized study reports
• Awareness and contribution to Preclinical submissions (e.g. IBs, INDs, OAs, PIPs, NDAs, MAAs etc.).
• Experienced in scientific writing (including reports) and data analysis, visualization and interpretation.
• Experienced in presenting key data at relevant meetings.
• Proficient in budgetary control.
• Experience of line management.
• Organisational skills and the ability to prioritise own and teams workload effectively.
• Ability to motivate and develop others.
• Effective written and verbal communication skills.
• Excellent attention to detail.
• Working knowledge of Excel, PowerPoint, Endnote, statistics, search engines and databases used for literature.
• Demonstrates a pragmatic approach to problem solving.
• Self-motivated approach, with a willingness to assist colleagues to achieve goals
• Embodies and models Jazz Pharmaceuticals core values (integrity, collaboration, passion, pursuit of excellence and innovation)

Jazz Pharmaceuticals is an Equal Opportunity Employer.

Please click here to apply.