Scientist, Nonclinical Development

Nonclinical Sciences        ·        South San Francisco, CA       ·       Full time 

At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration. Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

Would you like to take part in driving the development of new therapies that seek to transform patients’ lives? Do you desire both autonomy and collaboration in tackling scientific challenges that interest you? Would you like to be part of a hardworking team where everyone has a voice?

As an Associate Scientist or Scientist for the nonclinical development team focusing on bioassay development, you’ll work closely with scientists in Research, Development, Clinical and Regulatory teams to advance our drug discovery programs. You will be able to contribute across a variety of programs ranging from early research to clinical stage and have broad involvement in work central to Alector’s strategic goals. You will apply your existing technical skills, learn new skills, and play a key role in the nonclinical and clinical development of the programs and help grow the company. 

During the first year, your goals will include:

• Develop and qualify pharmacokinetic, pharmacodynamic, immunogenicity, and cell-based neutralizing antibody assays for various programs and perform PK and PD sample analysis supporting tox studies
• Summarize bioanalytical results, prepare and review technical reports in support of business development activities and regulatory filings
• Participate in regular cross-functional team meetings and present as needed

We’d love to hear from you if you have:

• A MSc or Ph.D. in Biology, Pharmacology, Immunology or a related subject with minimum of 3-5 years of industry experience ideally in assay development, cell culture and cell-based assays
• Experience in developing and/or validating pharmacokinetics, biomarkers, immunogenicity assays (ELISA, MSD ECL assays, Gyrolab immunoassays, etc.) for biologics, and cell-based assays for the detection of neutralizing antibodies to drug products
• Detailed understanding of the FDA’s and EMA’s regulatory guidance related to bioanalytical assays
• Excellent communication and writing skills and thrive in an environment where we work independently and on teams
• Proven a track record of learning new skills and troubleshooting independently and take pride in being self-motivate and efficient

#LI-MD1

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Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a treatment, where you’ll drive growth, this is your role. There is no limit to how far you can go with us.

Among the things you’ll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly-lit offices in the heart of the biotech area, flexible remote work options, and competitive compensation and benefits. But these matters only if you’re excited to build and own something great, and tackle these challenges with us. Come join us!

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief. 

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please click here to apply.