Vice President of Research and Development

Research & Development     ·      Boston, Massachusetts   ·       Full time

Company Overview

Reunion Neuroscience Inc., formerly the discovery division of Field Trip Health, is now a clinical stage pharmaceutical company pioneering bold, innovative science with the goal of making every mental health challenge not only treatable, but curable. Our approach is inspired by the promising results obtained with psychedelic molecules over the last few decades, including multiple controlled clinical trials demonstrating the potential to treat a wide variety of mental health conditions. Our proprietary approaches with serotonin agonists seek to make better, safer, more effective medicines in areas of unmet need. Our lead candidate, RE104, has a granted patent and is currently in Phase 1 Clinical Trial.

Role Overview

As Vice President (VP), Research and Development (R&D), and part of the scientific leadership of the company, this position requires a unique skill set with a foundation in chemistry and biological sciences, a strong understanding of drug development process as well as the rigors of compliance, as well as the ability to innovate. Reporting to the CSO, the VP of R&D must have the ability to multitask and shift between drug development, analytical and bioanalytical chemistry and aspects of early-stage and preclinical development including toxicology, drug metabolism, pharmacokinetics, pharmacodynamics all within the context of regulatory and quality strategy.

As the company functions on a remote-virtual pharma model, the successful candidate will have a strong track record of communications and vendor management skills, with successfully initiating, directing, and managing a broad range of studies across R&D in support of pipeline advancement for multiple indications with internal and external partners as well as exceptional cross-functional leadership skills to ensure constant alignment with internal project priorities and business goals, while being able to communicate effectively with academic and scientific peers as well as internal leadership.

What You’ll Do

• Key driver in creating and executing research strategies to advance lead and pipeline products from discovery into clinical development, providing the link between ideation to product development and clinical research.
• Lead and oversee all aspects of non-clinical testing, DMPK, drug development and manufacturing, testing, release, and stability, ensuring successful development of pipeline products and portfolio expansion.
• Build, lead and mentor internal development capability (team, resources, networks, budgets, etc.) in which leadership of projects is maintained internally, and external services and capabilities are used to drive projects forward. The goal is to develop a lean infrastructure that is effective, efficient, and successful.
• Identify, select, direct, and manage outsourced studies for the successful development of novel products. Oversee domestic and international CROs/CMOs for execution of outsourced GxP on Field Trip’s behalf. Strong understanding of ICH and GxP requirements for pharmaceutical development is required.
• Establish and maintain relationships with outside scientific experts in relevant disciplines to support the current and future planned R&D activities.
• Represent the company at scientific and industry meetings and describe the company’s products and research to internal and external stakeholders including partners, investors, collaborators, and regulatory agencies.

What you Bring to the Team

• PhD in Chemistry, Medicinal Chemistry, Pharmaceutical Sciences, or related field with 10+ years of industry experience.
• Strong scientific acumen and demonstrated ability to collaborate across multiple disciplines and manage vendors.
• Solid understanding of overall drug development strategies, spanning across development disciplines (non-clinical, clinical, CMC, RA/QA, commercial strategy, and development), and ideally, experience working in CNS indications in a startup company.
• A demonstrated track record in working in GLP, GMP environments in drug development and managing vendor compliance in collaboration with regulatory and quality teams.
• A track record of meeting and exceeding goals. Demonstrated ability to drive achievement and change as needed.
• Ability to anticipate future business needs in a fast-paced environment, and a commitment to continuous improvement and leadership.

Please click here to apply.