Vice President, Clinical Development Neurology

Clinical Science      ·        United States (Remote)       ·       Full time 

At Alector, our mission is to develop therapies that empower the immune system to combat neurodegeneration. Our team is solely focused on developing treatments for some of the most challenging diseases facing our society. We are supported in this mission by experienced and accomplished scientists and clinicians, leading healthcare investors, and pharma company partners who share in our commitment to bettering the lives of patients.

The Vice President of Clinical Development, Neurology will lead one or more development programs involving drug candidates in Alzheimer’s Disease, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis, and other diseases. You will be responsible for clinical strategies and plans for our lead molecules and help ensure the successful execution of our studies.

Reporting to the Senior Vice President of Clinical Development, the Vice President of Clinical Development will be a member of the Clinical development leadership team. The direct responsibilities of this position will cover all aspects of early clinical development Phase 1 and Phase 2 studies and may extend into Phase 3. This includes responsibility for advancing clinical programs through study planning and execution, development of biomarker strategies, as well as interpretation of data from these studies. You will interact with multiple levels of management within Alector, key external partners in the medical and scientific community, along global regulatory authorities.

The Vice President of Neurology has the following responsibilities:

• Provide leadership for programs that integrate the individual’s extensive knowledge in basic and clinical science, neurology disease areas with knowledge from the medical community around the world.
• Design and execute development programs in neurodegenerative diseases including AD, FTD, and ALS
• Manage the preparation and/or review of data listings, summary tables, study results, study reports, clinical/regulatory/safety documents, investigator brochures, and clinical development plans
• Integrate the scientific rationale, regulatory and payor requirements, input and advice from medical and patient advocacy groups, product development plan, and commercial goals to build a strategic framework for the Clinical Development Plan (CDP).
• Establish ambitious clinical development timelines, incorporating key decision points and Go/No Go criteria for each CDP.
• Develop and maintain collaborative relationships with program counterparts in Research, Regulatory, Biomarkers, Clinical Operations, and Biometrics for Clinical execution.
• Collaborate with Medical Affairs in developing educational materials and publication strategy.
• Engage with leaders, investigators, collaborative groups, and other specialists in scientific and clinical dialog around study design, study conduct, and interpretation of clinical results

You will have the following mix of professional and personal characteristics:

• Minimum 12+ years of Biotech/Pharmaceutical Industry experience, including 6+ years in Clinical Development; experience in rare diseases a plus
• Deep understanding of basic science related to neurodegeneration and immunology
• Capacity and willingness to work successfully across disease areas.
• Demonstrated leadership and team-building skills, including strong decision-making, conflict resolution, and analytical skills
• Demonstrated strategic and innovative thinking
• Excellent communication skills (oral and written) and organizational skills

Education:

• D. with Neurology training in degenerative CNS disorders preferred.

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Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a treatment, where you’ll drive growth, this is your role. There is no limit to how far you can go with us.

Among the things you’ll discover at Alector on Day 1 and throughout your tenure: Committed and driven colleagues, a bold and important company goal, brand-new brightly-lit offices in the heart of the biotech area, flexible remote work options, and competitive compensation and benefits. But these matters only if you’re excited to build and own something great, and tackle these challenges with us. Come join us!

At Alector, we believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Employees of Alector working on-site are required to be vaccinated against COVID-19, and are required to provide proof of vaccination. Employees may be entitled to an exception or reasonable accommodation if they cannot be vaccinated because of a disability/medical necessity, or sincerely held religious belief. 

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please click here to apply.