Postdoctoral Fellow – Protein Analytical Chemistry

Research & Development       ·        South San Francisco, California, United States of America       ·         Full time

The Position

We are seeking a highly motivated, independent researcher for a postdoctoral position in the Protein Analytical Chemistry Department at Genentech. This research will encompass the structural analysis of biotherapeutic proteins utilizing an emerging higher order structure (HOS) technique: Hydroxyl Radical Footprinting-Mass Spectrometry (HFR-MS). The selected candidate will play a key role in pioneering the advancement of HRF-MS in an industry setting. Potential applications include optimization of formulation development, comparability assessments, structure/function linkage, and epitope mapping. In addition, the candidate will be able drive their own ideas and collaborate across Genentech and Roche Global. This work will include a strong cross-functional collaboration with the multiple other Pharmaceutical Technical Development (PTD) and Genentech Early Research and Development (gRED) departments.

The successful candidate will be a recent PhD graduate in Biochemistry, Chemical Biology, Structural Biology or a related discipline. A strong publication record should provide evidence of productive, independent contributions in science. The applicant must have demonstrated expertise in protein characterization using LC-MS analysis in areas such as native MS, ion mobility MS, post-translational modifications, cell-based biomarkers, and/or bottom-up MS technologies (HRF-MS and/or Hydrogen/Deuterium Exchange).  Prior experience with protein structure determinations and computational structural rendering is highly desirable. Applied applications of MS with cell-based systems is the most relevant skill set, but not a requirement. The successful candidate must be highly self-motivated, capable of working independently, have excellent oral and written communication skills, and enjoy working in a collaborative setting.

Relocation benefits are available for this job posting

For information about the Postdoctoral Program at Genentech, please go to www.gene.com/careers/academic-programs/postdocs

#LI-PL1

#postdoc

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote.  If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.

Job Facts

Job Sub Category: postdocs
Schedule: full time
Job type: temporary (fixed term)
Posted date: Aug 1st 2022
Job id: 202207-129369

Beginning September 30, 2021, Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date.  This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote.  If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation. 

Please click here to apply.