In Vivo Research Scientist

Research & Development      ·        San Diego, CA          ·      Full time

Job ID: 355645BR

Job Title: Research Scientist, Neuroscience and Gene Therapies

Job Description

Over 900+ clinical trials validate that gene therapies are transforming the practice of medicine.

Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological genetic diseases? Novartis is advancing cutting-edge science, starting with our proprietary gene therapy for the treatment of spinal muscular atrophy (SMA). We are in the midst of an incredible journey and are looking for passionate individuals to join us on this important mission.
Novartis is dedicated to developing and commercializing novel treatments for patients suffering from rare and life-threatening neurological genetic diseases. Our initial product is a proprietary gene therapy approved by the US Food and Drug Administration for the treatment of pediatric patients with SMA. In addition to developing a treatment for SMA, Novartis also plans to develop other novel treatments for rare neurological diseases, including Rett syndrome and a Friedreich’s ataxia.

The Research Scientist I, Vivarium, is responsible for animal care and handling including running behavioral studies, dosing and executing in vivo experiments, and tissue collection under the supervision of scientists in support of pipeline development.

What you’ll be doing:

• Execute behavioral testing.
• Perform more high-level tasks necessary for the study of rodent models of disease such as animal identification by marking, breeding, weaning, and collection of tissue samples for DNA or RNA analysis.
• Organize, schedule, and execute experimental work.
• Examine data and prepare technical reports, summaries, and protocols, and quantitative analysis, ensuring experiments are well documented and comply with regulatory requirements. Assist in troubleshooting.
• Maintain and ensure safe laboratory environment and work practices. Follow standard operating procedures (SOP) and IACUC protocols. Help maintain laboratory and order common supplies.
• Ability to work collaboratively across a dynamic scientific environment, therefore excellent communication skills, both written and verbal, and strong interpersonal skills.
• Other related duties as assigned.

The pay range for this position at commencement of employment is expected to be between $63,000 and $94,000 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

https://www.novartis.com/careers/careers-research/notice-all-applicants-us-job-openings

EEO Statement

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum requirements

What you will bring to the role:

• Bachelor’s degree in biomedical research, neuroscience, animal behavior, animal sciences, or similar with 0-2 years related experience or 6 years of equivalent education/experience may be accepted.
• Minimum 1 year experience in mouse handling.
• Proficiency with standard in vivo techniques in rodents, including dosing and sampling routes (e.g., po, ip, sc, iv dosing; cardiac bleeds; necropsy and organ harvest).
• Experience running rodent behavioral studies.
• Preferred – Experience with survival stereotaxic surgeries in anesthetized animals including proper pre- and post-op care.
• Excellent oral and written communication skills.
• Preferred – Previous industry experience.

Why Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what’s possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!

Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please send an e-mail to tas.nacomms@novartis.com or call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network (https://talentnetwork.novartis.com/network).

Division: NIBR
Business Unit: NEUROSCIENCE
Country: USA
Work Location: San Diego, CA
Company/Legal Entity: NIBRI
Functional Area: Research & Development
Job Type: Full Time
Employment Type: Regular
Shift Work: No
Early Talent: No

Please click here to apply.