Postdoctoral Fellow – Translational Medicine & Oncology Bioinformatics, Shi & Yao Labs

Postdocs              ·            South San Francisco, California, United States of America          ·         Full time

Postdoctoral Fellow – Translational Medicine & Oncology Bioinformatics, Shi & Yao Labs

• South San Francisco, California, United States of America
• Full time

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The Position:

We are seeking a talented researcher with expertise in both experimental and computational techniques for a joint postdoctoral position in the Department of Translational Medicine Oncology (mentor: Dr. Zhen Shi) and the Department of Oncology Bioinformatics (mentor: Dr. Xiaosai Yao) at Genentech. The candidate will utilize molecular, cellular and computational biology, along with state-of-the-art single-cell technologies, to study translational control and protein homeostasis in the context of drug resistance.

As a postdoctoral scientist, your project will focus on:

1. Investigating the rewiring of protein synthesis in the context of resistance to KRAS inhibitor treatment.
2. Exploring how trans- and cis-regulatory elements interact to coordinate mRNA translation and contribute to drug resistance.
3. Examining the consequences of protein synthesis rewiring on protein homeostasis, stress response, and the identification of new vulnerabilities in tumor cells.

The candidate will become a member of the Genentech postdoctoral training program that provides an opportunity to pursue fundamental questions related to human health. Our successful postdoctoral fellows have successfully transitioned into careers in both industry and academia.

Qualifications:

• D. in Cancer/Molecular/Cell biology/Genetics, computational biology, or a related field
• Strong hands-on experience in laboratory research with molecular and cellular biology techniques
• Proficiency with analysis of high-throughput omics data
• One or more first-author papers published or accepted in a high-quality journal
• Highly motivated to conduct cutting-edge translational research that answers fundamental biological questions.

If you are an independent, vigorous, and collaborative researcher eager to contribute to groundbreaking discoveries, we invite you to apply and become an integral part of our dynamic research community.

More information about Dr. Zhen Shi & Dr. Xiaosai Yao Labs:

• https://www.gene.com/scientists/our-scientists/zhen-shi
• https://www.gene.com/scientists/our-scientists/xiaosai-yao

More Information about the Genentech Postdoctoral Program:

• https://www.gene.com/careers/university-and-early-career/postdocs   

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of California is $64,800 and $120,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below:

Benefits

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Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Job Facts

• Job Sub Category: Postdocs
• Schedule: Full time
• Job Type: Graduate / Post-Graduate (Fixed Term)
• Posted Date: Jan 3rd 2024
• Job ID: 202312-127037

Please click here to apply.