Who We Are:
At Neurocrine Biosciences – voted one of San Diego’s top places to work in 2018 – we pride ourselves on having a strong, distinctive and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose – to relieve patient suffering and enhance lives.

What We Do:
Neurocrine Biosciences is a biopharmaceutical company focused on developing treatments for neurological and endocrine related disorders.

About the Role:
The bioanalytical scientist will be responsible for conducting bioanalysis in support of discovery programs at Neurocrine Biosciences Inc (NBI) and will provide scientific/technical expertise to guide outsourcing assays at CROs. The scientist will possess deep scientific knowledge and technical experience in method development, optimization, troubleshooting LC-MS based bioanalytical assays. Depending on experience, this individual may determine pharmacokinetic parameters based on the bioanalytical results.

YOUR CONTRIBUTIONS (include, but are not limited to):

• • Method development and optimization of internal LC-MS/MS bioanalytical assays for drugs and metabolites from biological matrices (e.g. plasma, serum, urine and tissues)
  • Conduct bioanalytical measurements
  • Provide scientific advice for outsourcing assays
  • Maintenance, trouble-shooting, and optimization of instruments
  • If qualified, determine non-compartmental pharmacokinetic parameters
  • Document and summarize laboratory procedure and experimental results
  • Occasionally contribute to report finalization through preparation of figures and tables and providing QC reviews
  • Present data at inter and intra-departmental team meetings

REQUIREMENTS:

• • BS/ MS in chemistry or closely related field; minimum 5 years relevant industrial experience in a biotech, pharma, and/or CRO setting (or entry level PhD)
  • Demonstrated hands-on experience and technical knowledge in bioanalytical assays of small molecule therapeutics using mass spectrometry-based detection, such as
  • LC-MS/MS and LC-HRMS, and the ability to assist CROs in trouble-shooting assays.
  • Experience working in and accomplishing tasks a timeline driven setting.
  • Experience in lab automation is preferred
  • Experience in large molecules and biomarkers bioanalysis is beneficial
  • Understanding of regulatory and industry guidance, white papers and common practices pertaining to bioanalytical method validation and sample analysis is preferred
  • Good communication and presentation skills to effectively work with cross-functional groups with diverse background and interests
  • Strong attention to detail, excellent written and oral communication skills.
  • Ability to provide ideas for process improvements.Ability to work with a team of individuals to meet goals.

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

Please click here to apply.